CYP3A4Your two copies: *1/*1
Normal metabolizer
Both copies work normally.
Breaks down more prescription drugs than any other enzyme.
This result doesn't change the label.
Example report. Made from Leslie Knope's DNA data so you can see what yours will look like. Get your own report
AntipsychoticsExample report
Quetiapine
Seroquel
Use as directed
Your CYP3A4 gene works normally, so the standard dose of this drug is used.
The genes behind this label
The guidelines read one gene for quetiapine. Each card shows the two copies this person inherited and what they mean.
What the guidelines say
What each guideline says about your result.
CYP3A4Normal metabolizer
DPWG guideline
Evidence: moderateRead the guideline (Dutch Pharmacogenetics Working Group, opens in a new tab)
- In plain words
- Your CYP3A4 gene works normally, so the standard dose of this drug is used.
- What it means
- No clinically significant effect on quetiapine metabolism.
- What the guideline suggests
- Use standard quetiapine dosing.
About quetiapine
Quetiapine (Seroquel) is a second-generation antipsychotic used for schizophrenia and bipolar disorder, and in its extended-release form as an add-on treatment for major depression.
- Used for
- Schizophrenia; manic and depressive episodes of bipolar disorder; add-on treatment for major depressive disorder (extended-release only)
Others in antipsychotics
Compare all 12 antipsychoticsDon't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.