New Updates!

We've launched a new Starter Pharmacogenetics Report - caffeine, nicotine, alcohol, and ketamine, starting at $5.

We now support Whole Genome Sequencing (WGS) VCF files from providers like Nebula Genomics, Dante Labs, Sequencing.com, and Nucleus Genomics. Upload your VCF directly.

Genetics Driven Drug Guidance in Minutes

Transform your 23andMe, AncestryDNA, MyHeritage, or whole genome sequencing (WGS) data into actionable pharmacogenetics insights. Get personalized drug response reports for 103 medications without a doctor's prescription.

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103

Medications

23

Genes Analyzed

<1min

Results

$5

Starting at
Gene2Rx pharmacogenetics testing process: Upload genetic data from 23andMe, AncestryDNA, or MyHeritage to get personalized drug response report based on your DNA

What is Pharmacogenetics?

Pharmacogenetics (PGx) is the study of how individuals may respond differently to drugs based on their genetic makeup.

Your unique genetic profile affects how your body processes medications, potentially making them more or less effective, or causing unexpected side effects.

Did You Know?

Nearly everyone is affected by pharmacogenetics, but most people don't know it. Variability in your response to medications can be explained by your genetics.

Pharmacogenetics diagram showing how genetic variations in different people lead to different drug responses

Genes affect how individuals respond to drugs

Why it Matters

Pharmacogenetics affects nearly everyone, yet most people don't know how their genetics impact their medication response

Nearly Everyone Affected
99%

of people carry at least one pharmacogenetic variant that affects drug response

Clinical Relevance
1 in 5

people will be prescribed a drug for which they have altered PGx guidance

Real Impact

Your genetics can make drugs less effective or cause unwanted side effects

Common Medications with PGx Guidance

Many everyday medications are affected by your genetics. Here are some examples:

Antidepressants
Pain Killers
Epilepsy Drugs
Chemotherapies
Cholesterol Drugs
Recreational Drugs
View All 103 Medications

About Gene2Rx

We are PhD computational biologists specializing in pharmacogenetics research, dedicated to making personalized medicine and pharmacogenetic testing accessible to everyone

Transform Your Genetic Data Into Actionable Insights

We offer a comprehensive pharmacogenetic annotation service for 23andMe, AncestryDNA, and MyHeritage genetic data, transforming your existing genetic information into actionable drug response insights.

Get Started Now View Example Report
Evidence-Based

Latest peer-reviewed PGx guidance from CPIC and FDA

Comprehensive Coverage

103 medications across 31 drug classes

Rapid Processing

Get your report within minutes of uploading

Privacy & Security

We never sell your data and you can delete it anytime

Why Choose Gene2Rx?

Unlike GeneSight, Genomind, and other services, Gene2Rx offers direct-to-consumer access with faster results and broader coverage

Results in Minutes

Get your pharmacogenetics report in under 1 minute after upload. No waiting 2-3 weeks like with GeneSight or Genomind.

No Doctor Required

Order directly without needing a healthcare provider, unlike GeneSight and Genomind which require doctor authorization.

103 Medications

Analyze 103 medications across 31 drug classes. GeneSight and Genomind focus mainly on psychiatric medications only.

Affordable Pricing

Transparent, affordable pricing starting at $5. No insurance complexity or surprise bills that can exceed $100+ with competitors.

Already Have 23andMe, AncestryDNA, MyHeritage, or WGS Data?

Transform your existing genetic data into drug insights today

Consumer Genotyping Arrays

23andMe
AncestryDNA
MyHeritage

Upload the unmodified decompressed .txt file from your provider account.

Whole Genome Sequencing — VCF from any provider

Nebula Genomics
Dante Labs
Sequencing.com
Nucleus Genomics
DNA Complete
Veritas

Upload your .vcf or .vcf.gz — GRCh38 & hg19 both supported. +$15 per report for increased computational needs

Get Started Now

Important Disclaimer

Always consult your healthcare provider before making any changes to your medications or dosages.

Direct-to-consumer genetic data is not clinical grade. The information in our reports should be used only as a conversation starter with your healthcare provider to discuss appropriate clinical laboratory testing.

Gene2Rx does not condone the use or abuse of any prescription, over-the-counter, or illicit substances.

Gene2Rx Offerings

Get your results in minutes. Simply select the option that best fits your needs below, upload a copy of your genetic data, and your report will be ready in less than a minute.

Uploading a Whole Genome Sequencing (WGS) VCF? An additional $15 per report applies.

Starter Pharmacogenetics Report

$5
  • Covers Caffeine, Nicotine, Alcohol, and Ketamine
See example report
Buy Now

Complete Pharmacogenetics Report

$49
  • 103 medications with genetic drug testing
  • All 31 drug classes analyzed
  • Comprehensive PGx testing for Pain, Cardiac, Psychiatric, Recreational, and all other drug categories
See example report
Buy Now

Psychiatric Medication Pharmacogenetics

$35
  • 23 psychiatric medications with genetic analysis
  • Antidepressant genetic testing: SSRIs, SNRIs, TCAs, Antipsychotics, and Psychostimulants
See example report
Buy Now
Auto-Update Subscription
Add to any report — manage from your profile after purchase
$10 / year
  • Automatic report updates whenever a new version is released
  • No subscription? Update any report for 50% of its original price
  • Upgrade to Full Report at any time — credit applied for your prior purchase

Frequently Asked Questions

Everything you need to know about Gene2Rx pharmacogenetics testing

Gene2Rx analyzes your DNA and detects genetic variations that may lead to an atypical response to 103 medications, including antidepressants, pain medication, statins, alcohol, and other recreational drugs, among others. Each drug has guidance provided by the Food and Drug Administration or the Clinical Pharmacogenomics Implementation Consortium (CPIC). See here for a full list of analyzed medications.
Do not alter your medication dosage or stop taking your medication without first consulting your healthcare provider. Direct-to-consumer data is not clinical grade, so anything included in the report should be used as a conversation starter with your healthcare provider to seek the appropriate clinical laboratory test. Again, do not alter your medication dosage or stop taking your medication without first consulting your healthcare provider.
Our service relies on the genetic information provided to you by the direct-to-consumer service you paid for. Unfortunately, direct-to-consumer data is not clinical grade, so anything included in the report should be used as a conversation starter with your healthcare provider to seek the appropriate clinical laboratory test. DO NOT alter your medication dosage or stop taking your medication without first consulting your healthcare provider. Read more here and read primary research here.
Yes. For each drug included in the report either the FDA, CPIC, or both have deemed the evidence of a drug-gene interaction sufficient to provide clinical prescription guidance based on an individuals genetics. The Clinical Pharmacogenetics Implementation Consortium (CPIC) is a group of PGx experts that volunteer their time to curate genetic guidance for drug response, based on the most recent research. They have high standards for the evidence required to include a drug-gene guideline. You can read more about this organization on their website.
Consumer genotyping arrays: Among 23andMe, AncestryDNA, and MyHeritage, we recommend 23andMe. It directly measures more of the pharmacogenomically relevant variants, and our annotations perform best against 23andMe data based on internal validation.

Whole genome sequencing (WGS): Gene2Rx accepts VCF files from any WGS provider. Popular services include Nebula Genomics, Dante Labs, Sequencing.com, Nucleus Genomics, DNA Complete, and Veritas. If you have a 30x WGS VCF on hand — from any provider — you can upload it directly. WGS offers broader, higher-confidence variant coverage than consumer arrays and is our recommended input for the most accurate pharmacogenetics results.
Gene2Rx supports two categories of input:

Consumer genotyping arrays — download your raw data file:
• 23andMe: Download instructions
• AncestryDNA: Download instructions
• MyHeritage: Download instructions

Whole Genome Sequencing (WGS) VCF — upload directly:
We accept .vcf and .vcf.gz files from any WGS provider. The genome build (GRCh38 or hg19) is auto-detected from the VCF header. Popular providers include:
• Nebula Genomics
• Dante Labs
• Sequencing.com
• Nucleus Genomics
• DNA Complete, Veritas, and any other provider that delivers a standard VCF

A $15 WGS processing surcharge applies per report type.
Yes! Gene2Rx provides direct-to-consumer pharmacogenetics testing using your existing 23andMe, AncestryDNA, or MyHeritage genetic data — or a Whole Genome Sequencing (WGS) VCF file. No doctor visit, prescription, or healthcare provider authorization required. Simply upload your genetic data file and get your report in minutes.
Unlike GeneSight and Genomind, Gene2Rx doesn't require a doctor's prescription or healthcare provider authorization. You get results in minutes (not weeks), test 103 medications (not just psychiatric drugs), and pay transparent pricing ($5-$49) without insurance complications. GeneSight and Genomind focus primarily on mental health medications, while Gene2Rx covers pain, cardiac, psychiatric, and many other drug classes.
Yes! Check out our example reports to see if Gene2Rx is right for you. Each pricing option includes a link to view a sample report.
Please contact us at support@gene2rx.com to discuss bulk annotation of your data.

Get In Touch

Have questions? We're here to help!

Gene2Rx - Pharmacogenetics Testing Company Logo

We provide pharmacogenetic annotation services for direct-to-consumer genetic data.

Remember: DO NOT alter your medication dosage or stop taking your medication without first consulting your healthcare provider.

We are not affiliated with 23andMe, AncestryDNA, MyHeritage, the FDA, or the CPIC organization.

Contact Us

Need help or have questions? Reach out to our support team.

support@gene2rx.com
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