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Genetics-Driven Drug Insights in Under a Minute

Your drug response report. Ready in under a minute.

Upload your 23andMe, AncestryDNA, MyHeritage, TellMeGen, or whole genome sequencing (WGS) data and see how your genes may affect 120 medications. No new test and no doctor's prescription.

Get my report See an example report

Already took GeneSight or Genomind? Use those results

  • 120 medications
  • 27 genes analyzed
  • Full report $50
Gene2Rx Example, Psychiatric Report

Zoloft

sertraline

Your gene
CYP2C19 *1/*2
Result
Intermediate metabolizer
Implication
Your body processes sertraline more slowly, which may lead to higher levels in your blood.
Source
CPIC guideline for SSRIs (2023)
Usual starting dose Increase slowly Learn more

Illustrative results. Your results depend on your genes.

Works with the DNA file you already have

Download your raw data from your testing company's website and upload it here: no new test, no cheek swab, no waiting for a kit.

Don't see your provider? A raw genotype text file with the columns rsid chromosome position genotype (tab or comma separated) works too. Not sure about your file? Email support@gene2rx.com and we will take a look.

Consumer DNA tests
  • 23andMe
  • AncestryDNA
  • MyHeritage
  • TellMeGen
  • Genera

Or any provider that gives you a raw genotype file.

Whole genome sequencing
  • Nebula Genomics
  • Dante Labs
  • Sequencing.com
  • Nucleus Genomics
  • DNA Complete
  • Veritas

Upload your .vcf or .vcf.gz, GRCh38 or GRCh37. +$20 per report

Existing PGx test results

No file to upload: enter the genotypes from your report (such as CYP2D6 *1/*4) for a $20 Panel Report. Other clinical PGx reports that list star alleles work too.

Pick a report

Choose the report that fits your needs, upload your raw DNA data, and your report will be ready in minutes. One upload, one payment. Already have results from a PGx test? You can enter those instead.

Not sure which? Answer a few quick questions and we'll suggest one.

  • CPIC and FDA-based guidance
  • Results in minutes
  • Free sample report
  • Data never sold, delete anytime

  • Psychiatric

    28 medications

    $35with Pro

    28 psychiatric medications with genetic analysis: SSRIs, SNRIs, TCAs, antipsychotics, and psychostimulants.

    See example reportWhat's included

    Choose Psychiatric

  • Full

    Up to 120 medications

    $50with Pro

    Complete Pharmacogenetics Report: 120 medications across all 34 drug classes, including pain, cardiac, psychiatric and recreational drugs.

    See example reportWhat's included

    Choose Full

Uploading a whole genome sequencing (WGS) VCF? An additional $20 per report applies.

No DNA file? Have a GeneSight, Genomind, or other PGx report?

Enter the genotypes from your report and get a Gene2Rx Panel Report covering every medication those genes affect. How it works

$20 Enter my results

No DNA test at all? Join the waitlist for a Gene2Rx DNA test or learn which test works best for pharmacogenetics.

Pro, $30 a year: your report moves to each new version automatically, and you get medication tracking and the Report Assistant. About Pro

Always consult your healthcare provider before changing any medication or dosage. Direct-to-consumer genetic data is not clinical grade; use your report only as a conversation starter to discuss appropriate clinical laboratory testing. Gene2Rx does not condone the use or abuse of any prescription, over-the-counter, or illicit substances.

What is pharmacogenetics?

Pharmacogenetics (PGx) is the study of how your genes change the way you respond to medications: whether a standard dose works as expected, does too little, or causes side effects.

  • 99%

    of people carry at least one pharmacogenetic variant that affects drug response Source

  • 1 in 5

    people will be prescribed a drug for which they have altered PGx guidance Source

Why choose Gene2Rx?

Built by PhD computational biologists who specialize in pharmacogenetics. Compared with GeneSight and Genomind:

  • Results in minutes, not the 2 to 3 weeks a lab test takes.
  • No doctor required. Order directly, without a prescription or provider authorization.
  • 120 medications across 34 drug classes, not mainly psychiatric ones. See the list
  • One-time price. The Psychiatric report is $35 and the Full report $50. No insurance needed.
  • Evidence-based. Peer-reviewed guidance from CPIC and the FDA.

Read the full Gene2Rx vs GeneSight comparison

Already have a GeneSight or Genomind report? Use your results

Gene2Rx Pro

Manage every medication, not just your report

Managing more than one medication is one of the most common reasons people get Gene2Rx. Your medications don't act in isolation. One drug can change how your body processes another, an effect called phenoconversion, sometimes making a standard dose too strong or too weak. Gene2Rx Pro checks your whole medication list against your own genetic results, right here on the web.

  • Track your medications, doses, and schedule in one place
  • Drug-interaction and phenoconversion analysis across your whole list
  • When there is more than one drug for the same job, see which options your genetics flag and which they don't
  • The Report Assistant and automatic updates to the latest report version
  • Your report stays up to date as science learns more about how genetics affects drug response
Explore Gene2Rx Pro Learn how phenoconversion works

Included with Gene2Rx Pro, $30 per year. Cancel anytime.

ExampleCYP2D6 and codeine
CYP2D6 metabolizer status
Normal metabolizer Activity score 2.0.
Codeine pain relief
Use as directed Processed normally into its active form.

A simplified example. Pro runs this check across every gene and drug in your own report.

Explore pharmacogenetics by medication, gene, or class

Free, no sign-up. Learn which of your medications are affected by genetics before you order your report.

Or start with a category

View all 120 medications

Frequently asked questions

What people most often ask before they order.

What medications are included in my report?

Gene2Rx analyzes your DNA and detects genetic variations that may lead to an atypical response to 120 medications, including antidepressants, pain medication, statins, alcohol, and other recreational drugs, among others. Most have guidance from the Food and Drug Administration (FDA), the Clinical Pharmacogenetics Implementation Consortium (CPIC) or the Dutch Pharmacogenetics Working Group (DPWG). For a few substances without such guidance, such as caffeine, alcohol and GLP-1 medications, the report summarizes published research and labels it as Gene2Rx guidance. See here for a full list of analyzed medications.

Should I change medications or dosage based on my report?

Do not alter your medication dosage or stop taking your medication without first consulting your healthcare provider. Direct-to-consumer data is not clinical grade, so anything included in the report should be used as a conversation starter with your healthcare provider to seek the appropriate clinical laboratory test.

Why shouldn't I change my medication based on this report?

Our service relies on the genetic information provided to you by the direct-to-consumer service you paid for. Unfortunately, direct-to-consumer data is not clinical grade, so anything included in the report should be used as a conversation starter with your healthcare provider to seek the appropriate clinical laboratory test. Please don't change a dose or stop a medication without talking to your healthcare provider first. Read more here and read primary research here.

Are these expert annotations?

Yes. Gene2Rx's expert reviewers curate annotations from CPIC, FDA and Dutch Pharmacogenetics Working Group (DPWG) guidance and from published research. Where those organizations do not provide guidance, our reviewers assess the research and label the interpretation as Gene2Rx guidance. Each annotation identifies its source.

Do you recommend a particular genetic testing service?

Consumer genotyping arrays: In our testing, 23andMe, AncestryDNA and MyHeritage data gave very similar results, so use whichever you already have. The main gap is CYP2D6, which no consumer test reads as well as sequencing. See our guide to which DNA test to get.

Whole genome sequencing (WGS): Gene2Rx accepts VCF files from any WGS provider. Popular services include Nebula Genomics, Dante Labs, Sequencing.com, Nucleus Genomics, DNA Complete, and Veritas. If you have a 30x WGS VCF on hand from any provider, you can upload it directly. WGS offers broader, higher-confidence variant coverage than consumer arrays and is our recommended input for the most accurate pharmacogenetics results.

How do I get my genotype data?

Gene2Rx supports two categories of input:

Consumer genotyping arrays. Download your raw data file:

Whole Genome Sequencing (WGS) VCF. Upload it directly:
We accept .vcf and .vcf.gz files from any WGS provider. The genome build (GRCh38 or GRCh37) is auto-detected from the VCF header. Popular providers include:

Whole genome processing adds $20 per report.

Can I get pharmacogenetics testing without a doctor?

Yes! Gene2Rx provides direct-to-consumer pharmacogenetics testing using your existing 23andMe, AncestryDNA, MyHeritage, or TellMeGen genetic data, or a Whole Genome Sequencing (WGS) VCF file. No doctor visit, prescription, or healthcare provider authorization required. Simply upload your genetic data file and get your report in minutes.

How is Gene2Rx different from GeneSight or Genomind?

Unlike GeneSight and Genomind, Gene2Rx doesn't require a doctor's prescription or healthcare provider authorization. You get results in minutes (not weeks), test 120 medications (not just psychiatric drugs), and pay transparent pricing ($5-$50) without insurance complications. GeneSight and Genomind focus primarily on mental health medications, while Gene2Rx covers pain, cardiac, psychiatric, and many other drug classes. See the full side-by-side comparison

Do you have an example report?

Yes! Check out our example reports to see if Gene2Rx is right for you. Each pricing option includes a link to view a sample report.

I already took GeneSight or Genomind. Can I use those results?

Yes. You don't need a new test or a raw DNA file. Enter the genotypes from your GeneSight, Genomind, or other pharmacogenetic test report (for example, CYP2D6 *1/*4) and Gene2Rx builds a Panel Report for $20. It covers every medication with CPIC, FDA, or DPWG guidance for the genes you enter, not just the ones on your original report. Genes you don't enter aren't assessed. See how it works.

Does Gene2Rx perform bulk annotation of genetic data?

Yes. We offer a pharmacogenomic annotation API for bulk and high-volume data processing, anchored to CPIC and FDA guidance. See our API & Bulk Annotation page, or contact us at support@gene2rx.com.

Can clinics and labs partner with Gene2Rx?

Yes. We're developing partnerships with telehealth clinics that want to offer pharmacogenetic reports under their own brand, and with labs that need interpretation of their genotyping or sequencing data. We work with each partner to agree on branding, how results are delivered, and pricing based on volume.

Learn more about partnerships for telehealth clinics or services for labs, or talk to us about a partnership.