CYP2D6Your two copies: *4/*4
Poor metabolizer
Neither copy works.
0.0 activity scoreTypical: 1.25 to 2.25Turns on or clears about 1 in 4 prescription drugs. These include many drugs for depression, pain and ADHD.
This result changes the label.
Example report. Made from Leslie Knope's DNA data so you can see what yours will look like. Get your own report
AntipsychoticsExample report
Aripiprazole Lauroxil
Aristada
Use with caution
Your body breaks down aripiprazole lauroxil more slowly than normal, causing higher levels of the drug in your system. A lower dose is recommended to reduce the risk of side effects.
The genes behind this label
The guidelines read one gene for aripiprazole lauroxil. Each card shows the two copies this person inherited and what they mean.
What the guidelines say
What each guideline says about your result.
CYP2D6Poor metabolizer
- In plain words
- Your body breaks down aripiprazole lauroxil more slowly than normal, causing higher levels of the drug in your system. A lower dose is recommended to reduce the risk of side effects.
- What it means
- Results in higher systemic concentrations. Dosage adjustment is recommended. Refer to FDA labeling for specific dosing recommendations.
- What the label suggests
- Adjust the dosage as the FDA label directs for CYP2D6 poor metabolizers.
About aripiprazole lauroxil
Aripiprazole lauroxil (Aristada) is a long-acting injection for schizophrenia in adults.
- Used for
- Schizophrenia in adults
Others in antipsychotics
Compare all 12 antipsychoticsDon't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.