CYP2D6Your two copies: *4/*4
Poor metabolizer
Neither copy works.
0.0 activity scoreTypical: 1.25 to 2.25Turns on or clears about 1 in 4 prescription drugs. These include many drugs for depression, pain and ADHD.
This result changes the label.
Example report. Made from Leslie Knope's DNA data so you can see what yours will look like. Get your own report
AntipsychoticsExample report
Perphenazine
Trilafon
Use with caution
Your body breaks down perphenazine much more slowly than normal, causing the drug to build up in your system. This increases your risk of side effects.
The genes behind this label
The guidelines read one gene for perphenazine. Each card shows the two copies this person inherited and what they mean.
What the guidelines say
What each guideline says about your result.
CYP2D6Poor metabolizer
- In plain words
- Your body breaks down perphenazine much more slowly than normal, causing the drug to build up in your system. This increases your risk of side effects.
- What it means
- Results in higher systemic concentrations and higher adverse reaction risk.
- What the label suggests
- No specific dosing change in the FDA table. Refer to FDA labeling.
Also an ingredient in
Perphenazine is also in these combination products. The guidance above is for perphenazine on its own. What this person's genes mean for a combination is less clear, so if someone takes one, it's worth talking over with a prescriber or pharmacist.
About perphenazine
Perphenazine is an older (phenothiazine) antipsychotic used for schizophrenia and for severe nausea and vomiting in adults.
- Used for
- Schizophrenia; severe nausea and vomiting in adults
Others in antipsychotics
Compare all 12 antipsychoticsDon't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.