Example report. Made from Leslie Knope's DNA data so you can see what yours will look like. Get your own report

AntipsychoticsExample report

Iloperidone

Fanapt

Use with caution

Your body breaks down iloperidone much more slowly than normal, causing the drug to build up and increasing the risk of heart rhythm problems. The dose should be cut in half.

The genes behind this label

The guidelines read one gene for iloperidone. Each card shows the two copies this person inherited and what they mean.

CYP2D6*4/*4

Poor metabolizer

Neither copy works.

0.0 activity scoreTypical: 1.25 to 2.25

Turns on or clears about 1 in 4 prescription drugs. These include many drugs for depression, pain and ADHD.

This result changes the label.

What the guidelines say

What each guideline says about your result.

CYP2D6Poor metabolizer

FDA drug label

See the FDA table (U.S. Food and Drug Administration, opens in a new tab)

In plain words: Your body breaks down iloperidone much more slowly than normal, causing the drug to build up and increasing the risk of heart rhythm problems. The dose should be cut in half.
What it means: Results in higher systemic concentrations and higher adverse reaction risk (QT prolongation). Reduce dosage by 50%.
What the label suggests: Reduce the dosage by 50%.

About iloperidone

Iloperidone (Fanapt) is an antipsychotic for schizophrenia and for manic or mixed episodes of bipolar I disorder in adults.

Used for: Schizophrenia in adults; acute treatment of manic or mixed episodes of bipolar I disorder in adults

Others in antipsychotics

Compare all 12 antipsychotics

And 3 more

Don't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.

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