Example report. Made from Leslie Knope's DNA data so you can see what yours will look like. Get your own report
14 medications in this reportExample report
Antidepressants
SNRIs · SSRIs · Tricyclics
- Consider alternative 8
- Use with caution 6
The genes behind these labels
- CYP2D6Poor metabolizer*4/*4 · Changes the guidance for 11 of 11
- CYP2C19Intermediate metabolizer*1/*2 · Changes the guidance for 8 of 8
- CYP2B6Normal metabolizer*1/*1 · Read for 1, changes none
The antidepressants by label
Open any medication for the results behind its label and the guidelines in full.
Consider alternative 8 medications
- VenlafaxineEffexor XR SNRIs Consider alternative Your body breaks down this drug much more slowly, which has been linked to more side effects. A different antidepressant may be a better choice.CYP2D6Poor metabolizer
- AmitriptylineElavil Tricyclics Consider alternative Your two genes together change how your body handles this drug. It may cause more side effects or not work as well, so a different antidepressant is often suggested.CYP2D6Poor metabolizerCYP2C19Intermediate metabolizer
- ClomipramineAnafranil Tricyclics Consider alternative Your two genes together change how your body handles this drug. It may cause more side effects or not work as well, so a different antidepressant is often suggested.CYP2D6Poor metabolizerCYP2C19Intermediate metabolizer
- DesipramineNorpramin Tricyclics Consider alternative Your body breaks down this drug much more slowly, so it can build up and cause side effects. A different medicine is usually suggested.CYP2D6Poor metabolizer
- DoxepinSinequan, Quitaxon, Aponal Tricyclics Consider alternative Your two genes together change how your body handles this drug. It may cause more side effects or not work as well, so a different antidepressant is often suggested.CYP2D6Poor metabolizerCYP2C19Intermediate metabolizer
- ImipramineTofranil Tricyclics Consider alternative Your two genes together change how your body handles this drug. It may cause more side effects or not work as well, so a different antidepressant is often suggested.CYP2D6Poor metabolizerCYP2C19Intermediate metabolizer
- NortriptylinePamelor Tricyclics Consider alternative Your body breaks down this drug very slowly, so it builds up and side effects are more likely. A different drug is usually suggested.CYP2D6Poor metabolizer
- TrimipramineSurmontil Tricyclics Consider alternative Your two genes together change how your body handles this drug. It may cause more side effects or not work as well, so a different antidepressant is often suggested.CYP2D6Poor metabolizerCYP2C19Intermediate metabolizer
Use with caution 6 medications
- CitalopramCelexa SSRIs Use with caution Your body may break down the drug more slowly, increasing side effects. Your doctor may use a lower dose or adjust it more slowly.CYP2C19Intermediate metabolizer
- EscitalopramLexapro SSRIs Use with caution Your body may break down the drug more slowly, increasing side effects. Your doctor may use a lower dose or adjust it more slowly.CYP2C19Intermediate metabolizer
- FluvoxamineLuvox SSRIs Use with caution Your body breaks down this drug much more slowly. A lower starting dose, a slower increase, or a different drug may be safer.CYP2D6Poor metabolizer
- ParoxetinePaxil, Seroxat SSRIs Use with caution Your body processes this drug very slowly, so you may need half the usual dose to avoid side effects.CYP2D6Poor metabolizer
- SertralineZoloft SSRIs Use with caution Your body processes this drug a bit more slowly. You can start at the usual dose, but your doctor may raise it slowly, and a lower ongoing dose may be enough.CYP2C19Intermediate metabolizerCYP2B6Normal metabolizer
- VortioxetineTrintellix, Brintellix SSRIs Use with caution Your body clears this drug much more slowly. Half the usual starting dose is advised, or a different antidepressant.CYP2D6Poor metabolizer
Don't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.