Example report. Made from Leslie Knope's DNA data so you can see what yours will look like. Get your own report

Cardiovascular · AntiarrhythmicsExample report

Propafenone

Rythmol SR

Use with caution

Your body breaks down this drug much more slowly, so an irregular heartbeat is more likely. Some other drugs raise this risk even more.

The genes behind this label

The guidelines read one gene for propafenone. Each card shows the two copies this person inherited and what they mean.

Poor metabolizer

Neither copy works.

0.0 activity scoreTypical: 1.25 to 2.25

Turns on or clears about 1 in 4 prescription drugs. These include many drugs for depression, pain and ADHD.

This result changes the label.

What each guideline says about your result.

CYP2D6Poor metabolizer

FDA drug label

In plain words: Your body breaks down this drug much more slowly, so an irregular heartbeat is more likely. Some other drugs raise this risk even more.
What it means: Results in higher systemic concentrations and higher adverse reaction risk (arrhythmia). Avoid use in poor metabolizers taking a CYP3A4 inhibitor.
What the label suggests: Avoid use in poor metabolizers taking a CYP3A4 inhibitor.

Propafenone is a class IC antiarrhythmic used to keep atrial fibrillation and some other rhythm problems from coming back.

Used for: Preventing recurrences of symptomatic atrial fibrillation or paroxysmal supraventricular tachycardia in people without structural heart disease; life-threatening ventricular arrhythmias (tablets)

Don't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.