Example report. Made from Leslie Knope's DNA data so you can see what yours will look like. Get your own report
7 medications in this reportExample report
Cardiovascular
Antiarrhythmics · Antihypertensives · Beta Blockers · Blood Thinners · Cardiomyopathy
- Consider alternative 1
- Use with caution 6
The genes behind these labels
- CYP2D6Poor metabolizer*4/*4 · Changes the guidance for 3 of 3
- CYP2C19Intermediate metabolizer*1/*2 · Changes the guidance for 2 of 2
- CYP2C9Intermediate metabolizer*1/*2 · Changes the guidance for 1 of 1
- CYP4F2Intermediate metabolizer*1/*3 · Changes the guidance for 1 of 1
- NAT2Poor metabolizer*16/*5 · Changes the guidance for 1 of 1
- AGVKORC1Decreased expression-1639A/-1639G · Changes the guidance for 1 of 1
The cardiovascular by label
Open any medication for the results behind its label and the guidelines in full.
Consider alternative 1 medication
Use with caution 6 medications
- PropafenoneRythmol SR Antiarrhythmics Use with caution Your body breaks down this drug much more slowly, so an irregular heartbeat is more likely. Some other drugs raise this risk even more.CYP2D6Poor metabolizer
- HydralazineApresoline Antihypertensives Use with caution Your body breaks down hydralazine slowly, which means you need a lower starting dose. Higher doses may increase side effects, including a rare immune reaction.NAT2Poor metabolizer
- CarvedilolCoreg, Coreg CR Beta Blockers Use with caution Your body breaks down carvedilol much more slowly than normal, causing the drug to build up in your system. This increases your risk of dizziness and other side effects.CYP2D6Poor metabolizer
- MetoprololLopressor, Toprol XL Beta Blockers Use with caution Your body clears this drug very slowly, so it can build up. Your doctor may start with the lowest dose and watch your heart rate.CYP2D6Poor metabolizer
- WarfarinCoumadin Blood Thinners Use with caution Your genes suggest a lower dose may be safer. Your doctor can decide.CYP2C9Intermediate metabolizerVKORC1Decreased expressionCYP4F2Intermediate metabolizer
- MavacamtenCamzyos Cardiomyopathy Use with caution Your body breaks down mavacamten slightly slower than normal, which may lead to higher drug levels. Your doctor will monitor you closely and adjust the dose based on your response.CYP2C19Intermediate metabolizer
Don't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.