CYP2D6Your two copies: *4/*4
Poor metabolizer
Neither copy works.
0.0 activity scoreTypical: 1.25 to 2.25Turns on or clears about 1 in 4 prescription drugs. These include many drugs for depression, pain and ADHD.
This result changes the label.
Example report. Made from Leslie Knope's DNA data so you can see what yours will look like. Get your own report
Pain managementExample report
Pitolisant
Wakix
Use with caution
Your body breaks down pitolisant much more slowly than normal, causing the drug to reach higher levels in your system. The lowest starting dose is recommended to reduce the risk of side effects.
The genes behind this label
The guidelines read one gene for pitolisant. Each card shows the two copies this person inherited and what they mean.
What the guidelines say
What each guideline says about your result.
CYP2D6Poor metabolizer
- In plain words
- Your body breaks down pitolisant much more slowly than normal, causing the drug to reach higher levels in your system. The lowest starting dose is recommended to reduce the risk of side effects.
- What it means
- Results in higher systemic concentrations. Use lowest recommended starting dosage. Refer to FDA labeling for specific dosing recommendations.
- What the label suggests
- Use the lowest recommended starting dosage. Refer to FDA labeling.
About pitolisant
Pitolisant (Wakix) treats excessive daytime sleepiness and cataplexy in people 6 and older with narcolepsy.
- Used for
- Excessive daytime sleepiness or cataplexy in people 6 and older with narcolepsy
Others in pain management
Compare all 13 pain managementDon't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.