CYP2C9Your two copies: *1/*2
Intermediate metabolizer
One copy works and one works less well.
1.5 activity scoreTypical: 2Clears warfarin, phenytoin, celecoxib and some other pain relievers.
This result changes the label.
Example report. Made from Leslie Knope's DNA data so you can see what yours will look like. Get your own report
Pain managementExample report
Meloxicam
Mobic
Use with caution
Your body breaks down meloxicam slightly slower than normal. While there is no specific FDA guidance, your doctor may want to monitor you for side effects.
The genes behind this label
The guidelines read one gene for meloxicam. Each card shows the two copies this person inherited and what they mean.
What the guidelines say
What each guideline says about your result.
CYP2C9Intermediate metabolizer (activity score 1.5)
CPIC guideline
Use as directed Evidence: moderateRead the guideline (Clinical Pharmacogenetics Implementation Consortium, opens in a new tab)
- In plain words
- Your body slows the drug slightly, but usually the normal starting dose is fine.
- What it means
- Mildly reduced metabolism
- What the guideline suggests
- Initiate therapy with recommended starting dose. In accordance with the meloxicam prescribing information, use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals.
FDA drug label
Use with caution See the FDA table (U.S. Food and Drug Administration, opens in a new tab)
- In plain words
- Your body breaks down meloxicam slightly slower than normal. While there is no specific FDA guidance, your doctor may want to monitor you for side effects.
- What it means
- No FDA guidance for this phenotype
- What the label suggests
- Initiate therapy with recommended starting dose.
Also an ingredient in
Meloxicam is also in these combination products. The guidance above is for meloxicam on its own. What this person's genes mean for a combination is less clear, so if someone takes one, it's worth talking over with a prescriber or pharmacist.
About meloxicam
Meloxicam (Mobic) is a once-daily prescription nonsteroidal anti-inflammatory drug (NSAID) for osteoarthritis and rheumatoid arthritis.
- Used for
- Tablets: osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis in children who weigh at least 60 kg. Symbravo: acute migraine. Zynrelef: pain for up to 72 hours after certain operations. Injections: moderate to severe pain in adults.
Others in pain management
Compare all 13 pain managementDon't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.