CYP2C9Your two copies: *1/*2
Intermediate metabolizer
One copy works and one works less well.
1.5 activity scoreTypical: 2Clears warfarin, phenytoin, celecoxib and some other pain relievers.
This result doesn't change the label.
Example report. Made from Leslie Knope's DNA data so you can see what yours will look like. Get your own report
Pain managementExample report
Flurbiprofen
Ansaid, Ocufen, Strefen
Use as directed
Your body slows the drug down slightly, but usually the normal starting dose is fine.
The genes behind this label
The guidelines read one gene for flurbiprofen. Each card shows the two copies this person inherited and what they mean.
What the guidelines say
What each guideline says about your result.
CYP2C9Intermediate metabolizer (activity score 1.5)
CPIC guideline
Use as directed Evidence: moderateRead the guideline (Clinical Pharmacogenetics Implementation Consortium, opens in a new tab)
- In plain words
- Your body slows the drug down slightly, but usually the normal starting dose is fine.
- What it means
- Mildly reduced metabolism
- What the guideline suggests
- Initiate therapy with recommended starting dose. In accordance with the prescribing information, use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals.
FDA drug label
Use as directed See the FDA table (U.S. Food and Drug Administration, opens in a new tab)
- In plain words
- Your body may break down this drug a little slower than average. The FDA label gives no dose change for your result.
- What it means
- No FDA guidance for your genotype
- What the label suggests
- Initiate therapy with recommended starting dose.
About flurbiprofen
Flurbiprofen is a prescription nonsteroidal anti-inflammatory drug (NSAID) taken as tablets for osteoarthritis and rheumatoid arthritis; it also comes as eye drops used during eye surgery and, in some countries, as throat lozenges.
- Used for
- Tablets: osteoarthritis and rheumatoid arthritis. Eye drops: keeping the pupil from narrowing during eye surgery. Lozenges: short-term relief of sore throat.
Others in pain management
Compare all 13 pain managementDon't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.