Example report. The whole genome example: a public genome from the 1000 Genomes Project, with CYP2D6 Structural Analysis, so you can see what yours will look like. Get your own report
14 medications in this reportExample report
Antidepressants
SNRIs · SSRIs · Tricyclics
- Consider alternative 9
- Use with caution 3
- Use as directed 2
The genes behind these labels
- CYP2D6Ultrarapid metabolizer*2/*2x2 · Changes the guidance for 9 of 11
- CYP2C19Intermediate metabolizer*1/*2 · Changes the guidance for 8 of 8
- CYP2B6Unable to determine*18+Unknown/*9 · Changes the guidance for 1 of 1
The antidepressants by label
Open any medication for the results behind its label and the guidelines in full.
Consider alternative 9 medications
- ParoxetinePaxil, Seroxat SSRIs Consider alternative Your body clears this drug very fast, so it may not work well. A different drug is usually suggested.CYP2D6Ultrarapid metabolizer
- VortioxetineTrintellix, Brintellix SSRIs Consider alternative Your body clears this drug very fast, so it may not work as well. A different antidepressant is often suggested, or a higher dose.CYP2D6Ultrarapid metabolizer
- AmitriptylineElavil Tricyclics Consider alternative Your two genes together change how your body handles this drug. It may cause more side effects or not work as well, so a different antidepressant is often suggested.CYP2D6Ultrarapid metabolizerCYP2C19Intermediate metabolizer
- ClomipramineAnafranil Tricyclics Consider alternative Your two genes together change how your body handles this drug. It may cause more side effects or not work as well, so a different antidepressant is often suggested.CYP2D6Ultrarapid metabolizerCYP2C19Intermediate metabolizer
- DesipramineNorpramin Tricyclics Consider alternative Your body breaks down desipramine much faster than normal, which may make the drug less effective. An alternative medication that is not affected by your CYP2D6 gene may be recommended.CYP2D6Ultrarapid metabolizer
- DoxepinSinequan, Quitaxon, Aponal Tricyclics Consider alternative Your two genes together change how your body handles this drug. It may cause more side effects or not work as well, so a different antidepressant is often suggested.CYP2D6Ultrarapid metabolizerCYP2C19Intermediate metabolizer
- ImipramineTofranil Tricyclics Consider alternative Your two genes together change how your body handles this drug. It may cause more side effects or not work as well, so a different antidepressant is often suggested.CYP2D6Ultrarapid metabolizerCYP2C19Intermediate metabolizer
- NortriptylinePamelor Tricyclics Consider alternative Your body breaks down nortriptyline much faster than normal, which means the drug may not reach effective levels. A different antidepressant or a higher dose may be needed.CYP2D6Ultrarapid metabolizer
- TrimipramineSurmontil Tricyclics Consider alternative Your two genes together change how your body handles this drug. It may cause more side effects or not work as well, so a different antidepressant is often suggested.CYP2D6Ultrarapid metabolizerCYP2C19Intermediate metabolizer
Use with caution 3 medications
- CitalopramCelexa SSRIs Use with caution Your body may break down the drug more slowly, increasing side effects. Your doctor may use a lower dose or adjust it more slowly.CYP2C19Intermediate metabolizer
- EscitalopramLexapro SSRIs Use with caution Your body may break down the drug more slowly, increasing side effects. Your doctor may use a lower dose or adjust it more slowly.CYP2C19Intermediate metabolizer
- SertralineZoloft SSRIs Use with caution Your body processes this drug a bit more slowly. You can start at the usual dose, but your doctor may raise it slowly.CYP2C19Intermediate metabolizerCYP2B6Indeterminate
Use as directed 2 medications
- VenlafaxineEffexor XR SNRIs Use as directed Your body may break down this drug faster than usual, but no dose change is advised.CYP2D6Ultrarapid metabolizer
- FluvoxamineLuvox SSRIs Use as directed There is not enough data to know how your genetics affect response to this drug.CYP2D6Ultrarapid metabolizer
Don't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.