UGT1A1Your two copies: *1/*28+*60+*80
Intermediate metabolizer
One copy works and one works less well.
Clears bilirubin and some drugs, such as the cancer drug irinotecan.
This result doesn't change the label.
Example report. Made from Leslie Knope's DNA data so you can see what yours will look like. Get your own report
Oncology · ChemotherapiesExample report
Irinotecan
Camptosar, Onivyde
Use as directed
Your body breaks down irinotecan slightly slower than normal. The standard dose should work as expected.
The genes behind this label
The guidelines read one gene for irinotecan. Each card shows the two copies this person inherited and what they mean.
What the guidelines say
What each guideline says about your result.
UGT1A1Intermediate metabolizer
- In plain words
- Your body breaks down irinotecan slightly slower than normal. The standard dose should work as expected.
- What it means
- No FDA guidance for your genotype
- What the label suggests
- Initiate therapy with recommended starting dose.
About irinotecan
Irinotecan (Camptosar) is an intravenous chemotherapy drug for metastatic colorectal cancer, often given with fluorouracil and leucovorin.
- Used for
- Metastatic colorectal cancer (Camptosar); metastatic pancreatic cancer (Onivyde)
Others in oncology
Compare all 13 oncology- BelinostatBeleodaq Use as directed
- BelzutifanWelireg Use as directed
- CapecitabineXeloda, Xitabin, Kapetral Use as directed
- ErdafitinibBalversa Use as directed
- FluorouracilAdrucil, Carac Use as directed
- GefitinibIressa Use with caution
- MercaptopurinePurinethol Use as directed
- NilotinibTasigna Use as directed
Don't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.