Example report. The whole genome example: a public genome from the 1000 Genomes Project, with CYP2D6 Structural Analysis, so you can see what yours will look like. Get your own report
Lopressor, Toprol XL
Use as directed
Your body may clear metoprolol faster than usual, but there isn't enough evidence to know whether that changes how well it works, so there is no genetic recommendation.
The guidelines read one gene for metoprolol. Each card shows the two copies this person inherited and what they mean.
Ultrarapid metabolizer
One copy works normally and one works faster than usual.
3.0 activity scoreTypical: 1.25 to 2.25Turns on or clears about 1 in 4 prescription drugs. These include many drugs for depression, pain and ADHD.
This result doesn't change the label.
What each guideline says about your result.
CYP2D6Ultrarapid metabolizer
CPIC guideline
Read the guideline (Clinical Pharmacogenetics Implementation Consortium, opens in a new tab)
Metoprolol is also in these combination products. The guidance above is for metoprolol on its own. What this person's genes mean for a combination is less clear, so if someone takes one, it's worth talking over with a prescriber or pharmacist.
Metoprolol is a beta-blocker, sold as Lopressor, Toprol-XL and generics, that is used for high blood pressure, angina, heart failure and after a heart attack.
Don't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.
