Example report. The whole genome example: a public genome from the 1000 Genomes Project, with CYP2D6 Structural Analysis, so you can see what yours will look like. Get your own report

Cardiovascular · Beta BlockersExample report

Carvedilol

Coreg, Coreg CR

Use as directed

Your body processes carvedilol faster than most people, but there is no specific FDA guidance for your genotype. The standard dose is typically used.

The genes behind this label

The guidelines read one gene for carvedilol. Each card shows the two copies this person inherited and what they mean.

CYP2D6*2/*2x2

Ultrarapid metabolizer

One copy works normally and one works faster than usual.

3.0 activity scoreTypical: 1.25 to 2.25

Turns on or clears about 1 in 4 prescription drugs. These include many drugs for depression, pain and ADHD.

This result doesn't change the label.

What the guidelines say

What each guideline says about your result.

CYP2D6Ultrarapid metabolizer

FDA drug label

See the FDA table (U.S. Food and Drug Administration, opens in a new tab)

In plain words: Your body processes carvedilol faster than most people, but there is no specific FDA guidance for your genotype. The standard dose is typically used.
What it means: No FDA guidance for your genotype
What the label suggests: Initiate therapy with recommended starting dose.

About carvedilol

Carvedilol (Coreg, Coreg CR and generics) is a beta-blocker that also blocks alpha-1 receptors, used for heart failure, for a weak heart pump after a heart attack, and for high blood pressure.

Used for: Chronic heart failure; reduced heart pumping function after a heart attack; high blood pressure

Others in cardiovascular

Compare all 7 cardiovascular

Don't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.

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