Example report. The whole genome example: a public genome from the 1000 Genomes Project, with CYP2D6 Structural Analysis, so you can see what yours will look like. Get your own report
7 medications in this reportExample report
Cardiovascular
Antiarrhythmics · Antihypertensives · Beta Blockers · Blood Thinners · Cardiomyopathy
- Consider alternative 1
- Use with caution 3
- Use as directed 3
The genes behind these labels
- CYP2C19Intermediate metabolizer*1/*2 · Changes the guidance for 2 of 2
- CYP2C9Intermediate metabolizer*1/*8 · Changes the guidance for 1 of 1
- NAT2Intermediate metabolizer*4/*5 · Changes the guidance for 1 of 1
- CYP2D6Ultrarapid metabolizer*2/*2x2 · Read for 3, changes none
- CYP4F2Unable to determine*1/*2 · Read for 1, changes none
- GGVKORC1Normal expression-1639G/-1639G · Read for 1, changes none
The cardiovascular by label
Open any medication for the results behind its label and the guidelines in full.
Consider alternative 1 medication
Use with caution 3 medications
- HydralazineApresoline Antihypertensives Use with caution Your body breaks down hydralazine somewhat quickly. You will likely need a higher total daily dose to get a good effect.NAT2Intermediate metabolizer
- WarfarinCoumadin Blood Thinners Use with caution Your genes suggest a lower dose may be safer. Your doctor can decide.CYP2C9Intermediate metabolizerVKORC1Normal expressionCYP4F2Indeterminate
- MavacamtenCamzyos Cardiomyopathy Use with caution Your body breaks down mavacamten slightly slower than normal, which may lead to higher drug levels. Your doctor will monitor you closely and adjust the dose based on your response.CYP2C19Intermediate metabolizer
Use as directed 3 medications
- PropafenoneRythmol SR Antiarrhythmics Use as directed Your body processes propafenone faster than most people, but there is no specific FDA guidance for your genotype. The standard dose is typically used.CYP2D6Ultrarapid metabolizer
- CarvedilolCoreg, Coreg CR Beta Blockers Use as directed Your body processes carvedilol faster than most people, but there is no specific FDA guidance for your genotype. The standard dose is typically used.CYP2D6Ultrarapid metabolizer
- MetoprololLopressor, Toprol XL Beta Blockers Use as directed Your body may clear metoprolol faster than usual, but there isn't enough evidence to know whether that changes how well it works, so there is no genetic recommendation.CYP2D6Ultrarapid metabolizer
Don't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.