Example report. The whole genome example: a public genome from the 1000 Genomes Project, with CYP2D6 Structural Analysis, so you can see what yours will look like. Get your own report

Other substancesExample report

LSD

Acid

Use as directed

Your result suggests faster clearance of LSD, but no research has looked at this group.

The genes behind this label

The guidelines read one gene for LSD. Each card shows the two copies this person inherited and what they mean.

CYP2D6*2/*2x2

Ultrarapid metabolizer

One copy works normally and one works faster than usual.

3.0 activity scoreTypical: 1.25 to 2.25

Turns on or clears about 1 in 4 prescription drugs. These include many drugs for depression, pain and ADHD.

This result doesn't change the label.

What the guidelines say

What each guideline says about your result.

CYP2D6Ultrarapid metabolizer

Gene2Rx research summary

See the drug page (Gene2Rx research summaries, opens in a new tab)

In plain words: Your result suggests faster clearance of LSD, but no research has looked at this group.
What it means: Increased CYP2D6 activity, so faster LSD clearance is expected. The pooled clinical analysis compared participants with no functional CYP2D6 against carriers of functional CYP2D6 and did not examine ultrarapid metabolizers separately. This result cannot be produced from uploaded data, because increased-function CYP2D6 alleles are gene duplications, which are not detected.
What the research suggests: No genotype-based adjustment. Monitor participant-reported experiential responses.

About LSD

LSD is a semi-synthetic ergoline that produces its effects by activating serotonin 5-HT2A receptors.

Others in other substances

Compare all 7 other substances

Don't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.

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