Example report. The whole genome example: a public genome from the 1000 Genomes Project, with CYP2D6 Structural Analysis, so you can see what yours will look like. Get your own report

Other substancesExample report

Ketamine

Ketalar

Unable to determine

We cannot tell from this result how your genetics affect ketamine clearance.

The genes behind this label

The guidelines read one gene for ketamine. Each card shows the two copies this person inherited and what they mean.

CYP2B6*18+Unknown/*9

Unable to determine

One copy (*9) works less well. The other (*18) also carries a variant that doesn't match any known version of the gene. So we can't say how well CYP2B6 works overall.

Breaks down efavirenz, ketamine, methadone and some drugs for depression.

No clear result for this gene (see above), so its part in the label is unknown.

What the guidelines say

What each guideline says about your result.

CYP2B6Indeterminate

Gene2Rx research summary

See the drug page (Gene2Rx research summaries, opens in a new tab)

In plain words: We cannot tell from this result how your genetics affect ketamine clearance.
What it means: The alleles detected cannot be assigned a CYP2B6 function, so no phenotype can be inferred.
What the research suggests: A genotype-based dosing recommendation cannot be determined from this result.

About ketamine

Ketamine is an anaesthetic that works by blocking the NMDA glutamate receptor, and it is also used at lower doses for pain and, off label or as the related medicine esketamine, for depression.

Used for: As the sole anaesthetic for procedures not needing muscle relaxation, for induction of anaesthesia and to supplement other anaesthetics. It is a Schedule III controlled substance and is also used non-medically.

Others in other substances

Compare all 7 other substances

Don't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.

Back to the example report