Poor metabolizer
Neither copy works.
0.0 activity scoreTypical: 1.25 to 2.25Turns on or clears about 1 in 4 prescription drugs. These include many drugs for depression, pain and ADHD.
This result doesn't change the label.
Example report. Made from Leslie Knope's DNA data so you can see what yours will look like. Get your own report
Navoban
Use as directed
There is not enough evidence to know how your CYP2D6 result affects your response to tropisetron. CPIC makes no prescribing recommendation based on this result.
The guidelines read one gene for tropisetron. Each card shows the two copies this person inherited and what they mean.
Poor metabolizer
Neither copy works.
0.0 activity scoreTypical: 1.25 to 2.25Turns on or clears about 1 in 4 prescription drugs. These include many drugs for depression, pain and ADHD.
This result doesn't change the label.
What each guideline says about your result.
CYP2D6Poor metabolizer
CPIC guideline
No recommendationRead the guideline (Clinical Pharmacogenetics Implementation Consortium, opens in a new tab)
Tropisetron is a serotonin 5-HT3 receptor blocker used outside the United States to prevent nausea and vomiting, for example with cancer chemotherapy; no tropisetron product is approved by the FDA.
Don't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.