Example report. Made from Leslie Knope's DNA data so you can see what yours will look like. Get your own report

AntiemeticsExample report

Ondansetron

Zofran

Use as directed

There is not enough evidence to know how your CYP2D6 result affects your response to ondansetron. CPIC makes no prescribing recommendation based on this result.

The genes behind this label

The guidelines read one gene for ondansetron. Each card shows the two copies this person inherited and what they mean.

CYP2D6*4/*4

Poor metabolizer

Neither copy works.

0.0 activity scoreTypical: 1.25 to 2.25

Turns on or clears about 1 in 4 prescription drugs. These include many drugs for depression, pain and ADHD.

This result doesn't change the label.

What the guidelines say

What each guideline says about your result.

CYP2D6Poor metabolizer

CPIC guideline

No recommendationRead the guideline (Clinical Pharmacogenetics Implementation Consortium, opens in a new tab)

In plain words: There is not enough evidence to know how your CYP2D6 result affects your response to ondansetron. CPIC makes no prescribing recommendation based on this result.
What it means: Insufficient evidence demonstrating clinical impact
What the guideline suggests: No recommendation based on insufficient evidence

About ondansetron

Ondansetron (Zofran) prevents nausea and vomiting caused by cancer chemotherapy, radiation and surgery by blocking serotonin 5-HT3 receptors.

Used for: Preventing nausea and vomiting from cancer chemotherapy and radiotherapy, and after surgery

Others in antiemetics

Compare all 4 antiemetics

Don't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.

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