CYP2C9Your two copies: *1/*2
Intermediate metabolizer
One copy works and one works less well.
1.5 activity scoreTypical: 2Clears warfarin, phenytoin, celecoxib and some other pain relievers.
This result changes the label.
Example report. Made from Leslie Knope's DNA data so you can see what yours will look like. Get your own report
ImmunosuppressantsExample report
Siponimod
Mayzent
Use with caution
Your body breaks down siponimod slower than normal, causing the drug to reach higher levels in your system. Your doctor will need to adjust your dose based on your specific genetic profile.
The genes behind this label
The guidelines read one gene for siponimod. Each card shows the two copies this person inherited and what they mean.
What the guidelines say
What each guideline says about your result.
CYP2C9Intermediate metabolizer
- In plain words
- Your body breaks down siponimod slower than normal, causing the drug to reach higher levels in your system. Your doctor will need to adjust your dose based on your specific genetic profile.
- What it means
- Results in higher systemic concentrations. Adjust dosage based on genotype. Refer to FDA labeling for specific dosing recommendations.
- What the label suggests
- Adjust the dosage based on genotype as the FDA label directs.
About siponimod
Siponimod (Mayzent) is a daily tablet for relapsing forms of multiple sclerosis in adults.
- Used for
- Relapsing forms of multiple sclerosis in adults: clinically isolated syndrome, relapsing-remitting disease and active secondary progressive disease
Others in immunosuppressants
Compare all 4 immunosuppressantsDon't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.