CYP2D6Your two copies: *4/*4
Poor metabolizer
Neither copy works.
0.0 activity scoreTypical: 1.25 to 2.25Turns on or clears about 1 in 4 prescription drugs. These include many drugs for depression, pain and ADHD.
This result changes the label.
Example report. Made from Leslie Knope's DNA data so you can see what yours will look like. Get your own report
Movement disorders · Involuntary Movement ReducersExample report
Tetrabenazine
Xenazine
Use with caution
Your body breaks down tetrabenazine much more slowly than normal, causing the drug to reach higher levels in your system. A lower maximum dose is required to avoid side effects.
The genes behind this label
The guidelines read one gene for tetrabenazine. Each card shows the two copies this person inherited and what they mean.
What the guidelines say
What each guideline says about your result.
CYP2D6Poor metabolizer
- In plain words
- Your body breaks down tetrabenazine much more slowly than normal, causing the drug to reach higher levels in your system. A lower maximum dose is required to avoid side effects.
- What it means
- Results in higher systemic concentrations. The maximum recommended single dose is 25 mg and should not exceed 50 mg/day.
- What the label suggests
- The maximum single dose is 25 mg; do not exceed 50 mg a day.
About tetrabenazine
Tetrabenazine (Xenazine) treats the involuntary jerking movements (chorea) of Huntington's disease.
- Used for
- Chorea associated with Huntington's disease
Others in movement disorders
Compare all 3 movement disordersDon't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.