Is Mivacron affected by genetics?

Yes — the active ingredient is metabolized by a gene known to vary between individuals.

Relevant genes: BCHE

Mivacron is affected by pharmacogenetics through the BCHE gene. Your genotype for this gene can change how your body processes Mivacron, which can affect both how well it works and how well you tolerate it. The strongest evidence level on this page is Strong, based on CPIC or FDA guidelines.

What's in Mivacron

mivacurium affected by BCHE

Affected by BCHE · FDA · Strong evidence

Read the full mivacurium genetics guide →

Mivacurium phenotype recommendations

Published guidance from FDA on how mivacurium should be dosed or substituted based on your BCHE phenotype.

Phenotype	What it means	Recommendation	Evidence
Intermediate Metabolizer BCHE	Your genetic result suggests you may process this anesthetic more slowly, increasing the risk of prolonged muscle effects; your doctor may choose a different medicine.	FDA Avoid use of mivacurium or use with extreme caution and close monitoring; consider alternative agents.	Strong
Poor Metabolizer BCHE	Because your body processes this drug much more slowly, there’s a higher risk of long-lasting muscle effects; your doctor will likely choose another option.	FDA Avoid use of mivacurium; select alternative agents not affected by BCHE activity.	Strong
Normal Metabolizer BCHE	Your genetic result suggests you should process this medicine normally, but your doctor will manage dosing as usual.	FDA Initiate therapy with recommended starting dose and adjust per standard clinical practice.	Strong
Indeterminate BCHE	The impact of your genotype on response to this drug is unknown.	FDA Initiate therapy with recommended starting dose.	—
Not available BCHE	The impact of your genotype on response to this drug is unknown.	FDA Initiate therapy with recommended starting dose.	—

Source: FDA

Find out how your genetics affect Mivacron

This page describes the general pharmacogenetics. A Gene2Rx report analyzes your own DNA to tell you which metabolizer group you fall into, across every medication.

Get your report Look up another medication

Informational only — not medical advice. Pharmacogenetic guidance describes population-level patterns; your individual response depends on many factors. Never start, stop, or change a medication without talking to your prescribing clinician.