Example report. The whole genome example: a public genome from the 1000 Genomes Project, with CYP2D6 Structural Analysis, so you can see what yours will look like. Get your own report

UrologicalsExample report

Tolterodine

Detrol

Use as directed

Your CYP2D6 result means higher CYP2D6 activity than usual, but the FDA gives no genetic dosing change for tolterodine at this result.

The genes behind this label

The guidelines read one gene for tolterodine. Each card shows the two copies this person inherited and what they mean.

CYP2D6*2/*2x2

Ultrarapid metabolizer

One copy works normally and one works faster than usual.

3.0 activity scoreTypical: 1.25 to 2.25

Turns on or clears about 1 in 4 prescription drugs. These include many drugs for depression, pain and ADHD.

This result doesn't change the label.

What the guidelines say

What each guideline says about your result.

CYP2D6Ultrarapid metabolizer

FDA drug label

See the FDA table (U.S. Food and Drug Administration, opens in a new tab)

In plain words: Your CYP2D6 result means higher CYP2D6 activity than usual, but the FDA gives no genetic dosing change for tolterodine at this result.
What it means: No FDA guidance for your genotype
What the label suggests: Initiate therapy with recommended starting dose.

About tolterodine

Tolterodine (Detrol and generics) treats overactive bladder.

Used for: Overactive bladder with urge incontinence, urgency and frequency

Don't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.

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