Example report. Made from Leslie Knope's DNA data so you can see what yours will look like. Get your own report

UrologicalsExample report

Tolterodine

Detrol

Use with caution

Your body breaks down tolterodine more slowly than normal, causing it to build up in your system. This increases the risk of side effects, including heart rhythm problems.

The genes behind this label

The guidelines read one gene for tolterodine. Each card shows the two copies this person inherited and what they mean.

CYP2D6*4/*4

Poor metabolizer

Neither copy works.

0.0 activity scoreTypical: 1.25 to 2.25

Turns on or clears about 1 in 4 prescription drugs. These include many drugs for depression, pain and ADHD.

This result changes the label.

What the guidelines say

What each guideline says about your result.

CYP2D6Poor metabolizer

FDA drug label

See the FDA table (U.S. Food and Drug Administration, opens in a new tab)

In plain words: Your body breaks down tolterodine more slowly than normal, causing it to build up in your system. This increases the risk of side effects, including heart rhythm problems.
What it means: Results in higher systemic concentrations and higher adverse reaction risk (QT prolongation).
What the label suggests: No specific dosing change in the FDA table. Refer to FDA labeling.

About tolterodine

Tolterodine (Detrol and generics) treats overactive bladder.

Used for: Overactive bladder with urge incontinence, urgency and frequency

Don't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.

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