Example report. Made from Leslie Knope's DNA data so you can see what yours will look like. Get your own report

AnestheticsExample report

Succinylcholine

Quelicin, Anectine

Unable to determine

We couldn't check the genes for this anesthesia reaction from your data. This does not mean that a normal response is expected.

The genes behind this label

The guidelines read 3 genes for succinylcholine. Each card shows the two copies this person inherited and what they mean.

Not checked

We couldn't check this gene from your data. This does not mean that a normal response is expected.

A muscle channel. Rare changes in it can cause a dangerous reaction to some anesthetics.

Not checked in this report, so its part in the label is unknown.

Not checked

We couldn't check this gene from your data. This does not mean that a normal response is expected.

A muscle channel. Rare changes in it can cause a dangerous reaction to some anesthetics.

Not checked in this report, so its part in the label is unknown.

BCHEReference/Reference

Normal metabolizer

Both copies work normally.

Breaks down two muscle relaxers used in surgery. These are succinylcholine and mivacurium.

This result doesn't change the label.

What each guideline says about your result.

RYR1No resultCACNA1SNo result

CPIC guideline, both genes together

In plain words: We couldn't check the genes for this anesthesia reaction from your data. This does not mean that a normal response is expected.
What it means: Malignant hyperthermia susceptibility could not be determined.
What the guideline suggests: Clinical findings, family history and clinical evaluation should guide anesthesia decisions.

BCHENormal metabolizer

FDA drug label

In plain words: Your body breaks down this drug normally. Your doctor can use the usual dose.
What it means: Normal BCHE activity and expected metabolism of succinylcholine.
What the label suggests: Initiate therapy with recommended starting dose and adjust per standard clinical practice.

CPIC reads your RYR1 and CACNA1S results together for succinylcholine, so this label reflects both genes.

Succinylcholine (Anectine, Quelicin) is a fast-acting muscle relaxant used to place a breathing tube and to relax muscles during anesthesia.

Used for: Tracheal intubation and muscle relaxation during anesthesia, surgery or mechanical ventilation

Don't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.