CYP2D6Your two copies: *4/*4
Poor metabolizer
Neither copy works.
0.0 activity scoreTypical: 1.25 to 2.25Turns on or clears about 1 in 4 prescription drugs. These include many drugs for depression, pain and ADHD.
This result changes the label.
Example report. Made from Leslie Knope's DNA data so you can see what yours will look like. Get your own report
AntihistaminesExample report
Meclizine
Antivert
Use with caution
Your body breaks down meclizine much more slowly than normal, which may cause the drug to build up to higher levels and increase the risk of side effects. Close monitoring is recommended.
The genes behind this label
The guidelines read one gene for meclizine. Each card shows the two copies this person inherited and what they mean.
What the guidelines say
What each guideline says about your result.
CYP2D6Poor metabolizer
- In plain words
- Your body breaks down meclizine much more slowly than normal, which may cause the drug to build up to higher levels and increase the risk of side effects. Close monitoring is recommended.
- What it means
- May affect systemic concentrations. Monitor for adverse reactions and clinical effect.
- What the label suggests
- Monitor for adverse reactions and clinical effect.
About meclizine
Meclizine is an antihistamine prescribed for vertigo from inner-ear (vestibular) disorders and sold without a prescription for motion sickness.
- Used for
- Prescription: vertigo from diseases of the vestibular system in adults. Over the counter: preventing and treating nausea, vomiting and dizziness from motion sickness
Don't change a dose on your own. Bring this report to your prescriber or pharmacist. They can weigh it with everything else they know about you.